The terms »mind« and »matter« appear to signify two concepts irreplaceable and permanent in nature. The increasing challenges and modes of reflection of digital life and cultural creation have contributed to a productive doubting of said dichotomy. Net culture has exposed the causality of the two only superficially contradictory systems and translated these into new technological realities. This publication, using an interdisciplinary approach, strives to investigate the entanglement of cultural, artistic and technical praxis, to document the developments, to clarify the status quo of the scientific community in a practical and exemplary fashion and to enable glimpses of potential future developments.