This book constitutes the proceedings of the 8th International Conference on Intelligence Science and Big DataEngineering, IScIDE 2018, held in Lanzhou, China, in August 2018.The  59 full papers presented in this book were carefully reviewed and selected from 121 submissions.They are grouped in topical sections on robots and intelligent systems; statistics and learning; deep learning; objects and language; classification and clustering; imaging; and biomedical signal processing.