Analytical chemistry is experiencing a paradigm shift as fast development occurs in digital technologies, materials, and data integration. Microfluidics, devices using the Internet of Things (IoT), AI-assisted analysis, and portable sensing are some of the tools currently available in smart analytical chemistry that are transforming data capture, analysis, and use in every scientific and industrial field. Smart Analytical Chemistry explains to the readers how smart things and platforms are designed, fabricated and deployed, and how to integrate responsive materials, integrated electronics, and data processing in an analytical platform. It covers concepts, technologies, and practical implementations. It focuses on application-driven-innovation and describes case studies related to environmental monitoring, healthcare diagnostics, food safety and  industrial quality control. Filling the gap between the classical approaches and the modern intelligent systems, it helps readers rethink workflows and integrate technology, and provides sustainable data-driven solutions in science and industry.